Promethazine and codeine ought to be applied in the course of pregnancy only if the opportunity advantage justifies the likely hazard for the fetus.

This medication is prescribed for the existing condition only. Tend not to use it later on for an additional affliction unless informed to do so by your health practitioner. A special medication could possibly be required in Individuals conditions.

This products could have inactive ingredients, which may bring about allergic reactions or other difficulties. Speak with your pharmacist for more facts.

Dosage of codeine Really should not be Amplified if cough fails to respond; an unresponsive cough must be reevaluated in five days or faster for doable fundamental pathology, for instance foreign human body or lower respiratory tract condition.

Stimulation can be evident, specifically in kids and geriatric patients. Convulsions could rarely come about. A paradoxical-variety response has actually been reported in little ones acquiring one doses of seventy five mg to 125 mg orally, characterized by hyperexcitability and nightmares.

Absorption Codeine is absorbed from the gastrointestinal tract with greatest plasma concentration transpiring sixty minutes write-up administration. The existence of a higher-Extra fat, higher-calorie meal did not noticeably impression the PK of codeine.

Even though the danger of addiction in any personal is unidentified, it can take place in patients appropriately prescribed Promethazine HCl and Codeine Phosphate Oral Remedy. Habit can arise at recommended dosages and If your drug is misused or abused. Pitfalls are improved in people with a personal or loved ones heritage of compound abuse (including drug or alcohol abuse or addiction) or mental illness Promethazine codeine syrup (e.g., significant depression).

The combination of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric patients below six several years of age, simply because The mix may perhaps cause lethal respiratory despair In this particular age population.

This will take place Even though you take Promethazine Hydrochloride and Codeine Phosphate Oral Alternative specifically as prescribed by your healthcare service provider. Your chance of habit, abuse, and misuse is improved if you or simply a member of the family has a history of drug or Alcoholic beverages abuse or dependancy, or mental health problems.

If adrenal insufficiency is diagnosed, treat with physiologic substitution doses of corticosteroids. Wean the patient off of the opioid to permit adrenal purpose to Get better and continue corticosteroid treatment until finally adrenal perform recovers. Other opioids may very well be tried using as some cases noted usage of a special opioid devoid of recurrence of adrenal insufficiency. The knowledge readily available doesn't establish any individual opioids as getting far more prone to be connected to adrenal insufficiency.

Take this medication exactly as prescribed to lower the potential risk of habit. Talk to your medical professional or pharmacist For additional particulars.

Cure of Overdose Remedy of overdosage is pushed by the overall scientific presentation, and consists of discontinuation of Promethazine HCl and Codeine Phosphate Oral Solution together with establishment of appropriate therapy. Give Main notice to the reestablishment of satisfactory respiratory Trade through provision of the patent and guarded airway as well as the establishment of assisted or managed air flow.

Printed reports with codeine have claimed inconsistent conclusions and possess vital methodological constraints (see Knowledge). You'll find reviews of respiratory despair when codeine is applied through labor and shipping and delivery (see Clinical Things to consider).

The treatment method of overdosage with promethazine and codeine is basically symptomatic and supportive. Only in circumstances of utmost overdosage or personal sensitivity do important symptoms together with respiration, pulse, blood pressure level, temperature, and EKG must be monitored. Activated charcoal orally or by lavage can be presented, or sodium or magnesium sulfate orally being a cathartic. Awareness should be provided to your reestablishment of suitable respiratory Trade by means of provision of the patent airway and establishment of assisted or managed air flow.